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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1882L1 | Orphanin FQ(1-11) acetate(178249-41-7 free base) | Opioid Receptor | |
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays a... | |||
TP1071 | Nociceptin | Orphanin FQ | Opioid Receptor |
Nociceptin (Orphanin FQ) is a 17-amino-acid polypeptide that is structurally related to the opioid peptide dynorphin A. | |||
TP1882 | Orphanin FQ(1-11) | Orphanin FQ (1-11) | |
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays a... | |||
T75897 | Orphanin FQ(1-11) TFA | ||
Orphanin FQ(1-11) TFA, a fragment of orphanin FQ or nociceptin (OFQ/N), acts as a powerful NOP receptor (ORL-1; OP4) agonist, exhibiting a K i of 55 nM. It lacks affinity for μ, δ, κ1, and κ3 receptors (K i >1000 nM), de... | |||
TP1940L1 | Ac-RYYRIK-NH2 acetate | Opioid Receptor | |
Ac-RYYRIK-NH2 acetate is an agonist at nociceptin/orphanin FQ(noc/OFQ) receptors, affecting spontaneous locomotor activity. Ac-RYYRIK-NH2 acetate is a partial agonist on ORL1 transfected in CHO cells, antagonizes the sti... | |||
T23475 | Trap-101 hydrochloride | Trap 101 | Others |
nociceptin/orphanin FQ (NOP) receptor antagonist | |||
T26918 | BU08028 | BU 08028,BU-08028 | |
BU08028 is a mu opioid peptide (MOP) receptor and nociceptin-orphanin FQ peptide (NOP) receptor agonist. | |||
T21999 | (±)-J 113397 | ||
(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM). J-113397 inhibited nociceptin/orphanin FQ-stimulated GTPγS binding to CHO cells expressing ORL1 with an IC 50... | |||
TP1885 | [(pF)Phe4]Nociceptin(1-13)NH2 | ||
Highly potent and selective nociceptin/orphanin FQ receptor (OP4) agonist peptide (pKi = 10.68; pEC50 = 9.80). Displays > 8000-fold selectivity over δ, κ, and μ opioid receptors and has relatively long lasting pronocicep... | |||
T75909 | [Nphe1]Nociceptin(1-13)NH2 TFA | ||
[Nphe1]Nociceptin(1-13)NH2 is a novel endogenous ligand for the nociceptin/orphanin FQ (NC) receptor, acting as a selective and competitive antagonist without any agonist effects. It binds specifically to recombinant noc... | |||
T76420 | Nocistatin | ||
Nocistatin, an endogenous neuropeptide, serves as a ligand for the orphan opioid receptor-like receptor and functionally antagonizes the neuropeptide nociceptin/orphanin FQ (Noc/OFQ). It inhibits 5-HT release through a G... | |||
T75907 | Ac-RYYRIK-NH2 TFA | ||
Ac-RYYRIK-NH2 TFA acts as both a potent partial agonist for ORL1 when transfected in CHO cells (K d = 1.5 nM) and an endogenous ligand of ORL1. Moreover, it serves as a specific antagonist that inhibits G protein activat... |